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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBR1 All Species: 12.42
Human Site: S650 Identified Species: 27.33
UniProt: Q16650 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16650 NP_006584.1 682 74053 S650 A D T P V S E S S S P L K S E
Chimpanzee Pan troglodytes XP_526157 702 74704 N670 P S N S S N E N S P S I K C E
Rhesus Macaque Macaca mulatta XP_001093085 737 80029 N705 P S N S S N E N S P S I K C E
Dog Lupus familis XP_545492 682 73929 S650 A D T P V S E S S S P L K S E
Cat Felis silvestris
Mouse Mus musculus Q64336 681 73923 S649 A D T P V S E S S S P L K S E
Rat Rattus norvegicus Q5I2P1 517 57726 Y488 L Q P P E F L Y T H G V P R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514679 386 42515 S357 R R L S P Y D S S T D G S P P
Chicken Gallus gallus Q9PWE8 521 58384 L491 S L Q P A E F L Y S H G V P R
Frog Xenopus laevis P79944 692 75925 N662 P S T S S N E N S P P I K C E
Zebra Danio Brachydanio rerio Q9IAK8 492 55218 Y461 A G L Q G N E Y L Y A H G L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791266 946 105128 Q916 S F P S F P S Q P S T M N G Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49 46.8 99.2 N.A. 99.1 24.6 N.A. 30.3 24.4 50 25.5 N.A. N.A. N.A. N.A. 26.7
Protein Similarity: 100 64 60.5 99.5 N.A. 99.2 37.2 N.A. 38.1 36.5 65 37.5 N.A. N.A. N.A. N.A. 40.7
P-Site Identity: 100 26.6 26.6 100 N.A. 100 6.6 N.A. 13.3 13.3 40 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 46.6 46.6 100 N.A. 100 20 N.A. 26.6 20 60 26.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 37 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % C
% Asp: 0 28 0 0 0 0 10 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 10 10 64 0 0 0 0 0 0 0 55 % E
% Phe: 0 10 0 0 10 10 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 10 0 0 0 0 0 10 19 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 10 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 55 0 0 % K
% Leu: 10 10 19 0 0 0 10 10 10 0 0 28 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 19 0 0 37 0 28 0 0 0 0 10 0 0 % N
% Pro: 28 0 19 46 10 10 0 0 10 28 37 0 10 19 10 % P
% Gln: 0 10 10 10 0 0 0 10 0 0 0 0 0 0 10 % Q
% Arg: 10 10 0 0 0 0 0 0 0 0 0 0 0 10 10 % R
% Ser: 19 28 0 46 28 28 10 37 64 46 19 0 10 28 0 % S
% Thr: 0 0 37 0 0 0 0 0 10 10 10 0 0 0 10 % T
% Val: 0 0 0 0 28 0 0 0 0 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 19 10 10 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _